Why Are Elephants Considered For Cancer Research - 766 Words

Abeggien L, Caulin A, Chan A, Lee K, Robinson R, Campbell M, Kiso W, Schmitt D, Waddell P, Bhaskara S, Jensen S, Maley C, Schiffman J (2015) Potential Mechanisms for Cancer Resistance in Elephants and Comparative Cellular Response to DNA Damage in Humans. JAMA. 314(17):1850-1860.doi:10.1001/jama.2015.13134 Questions 1. Why were elephants considered for cancer research? 2. Why might elephants have evolved to be more resistant to cancers than other mammals? 3. Are there other mammals possessing multiple copies of p53 genes? 4. How is p53 expressed when there are multiple copies? 5. What are the implications of this research for medicine? The article states that the importance of the research is to gainâ€Å"insights into human physiology and pathophysiology, including tumor biology† through research of evolutionary medicine. The objective of the research as stated by the article is to â€Å"identify mechanisms for cancer resistance in elephants and compare cellular response to DNA damage among elephants, healthy human controls, and cancer-prone patients with Li-Fraumeni syndrome.† Persons with Li-Fraumeni syndrome have a 90% risk of cancer in their lifetime. Li-Fraumeni syndrome is an inherited autosomal dominant disorder in which the TP53 gene on one of the homologs of chromosome 17 is mutated usually passed on from a mutation in germ line cells. TP53 is a tumor suppressor gene which codes for p53, a nucleophosphoprotein that is able to bind toShow MoreRelatedEssay about The Ethics and Limitations of Animal Research 1550 Words   |  7 Pagesscience and medicine to develop so without animal research ( â€Å"The Use of Non-Human Animals in Research†, 2004). Nevertheless, do the human medical benefits really justify the animal suffering in animal research? If so, what should are the possible considerations and limitations related to the matter? It appears to be a challenge to find common ground concerning the above questions. This paper will first present the current guidelines of animal research, and what is being done to help preserve the sufferingRead MoreShould We Save Endangered Species?1740 Words   |  7 Pagesquestion why we should save a species from dying out. Isn t this part of the process of natural selection? Is there any environmental benefit to preserving a dying species? For some it s a question with an obvious answer, for others... it requires some thought. What benefit is there to saving an endangered species from dying out? This article outlines some of the arguments both for—and against—conservation of endangered species. Before we begin, a little background. A species is considered endangeredRead MoreThe Importance Of Animals For Animal Testing1754 Words   |  8 PagesAnimal research, also known as in vivo testing, is the use of animals for experiments. Experimentation on animals dates back to as early as 500 BC, making this form of medical education and research one of the most fundamental known to humans. Almost 400 years ago, a doctor named William Harvey used animals to discover how blood circulated in the body. This discovery is considered the spark of the scientific revolution in which many lives were saved all thanks to the help of animal testing. The modernRead MoreShould Physician -Assisted Suicide Be Legal?2498 Words   |  10 Pages2000). This paper will show why it is important for physician-assisted suicide to be legalized in all states and territories in order to assist the terminally ill and severely disabled patients who are not capable to take care of themselves and want to have a right die with dignity. Everyone has his or her own opinion about physician-assisted suicide, but what about the patients who have to suffer physically and mentally because of an incurable type of cancer or have a stroke that have leftRead More Veganism and a Sustainable Lifestyle Essay1929 Words   |  8 Pagespain, there is no reason for them to change their ways; however, many studies have been conducted that prove animals are both intelligent, and cognizant of pain. Though some make speciesist arguments that animals are too far below humanity to be considered â€Å"intelligent,† this is far from true – animals simply possess a slightly different intellectual skill-set than humans. While humanitys intelligence is linguistic, logical, and emotional for the most part, animals rely on their emotional and practicalRead MoreResearch Paradigm14392 Words   |  58 PagesQualitative, and Mixed Research LEARNING OBJECTIVES To be able to Describe the characteristics of quantitative research. List and explain the different types of variables used in quantitative research. Explain the difference between experimental and nonexperimental quantitative research. Explain the concept of a correlation coefficient. Describe the characteristics of qualitative research. List and explain the differences among the different types of qualitative research introduced in thisRead MoreDescriptive Essay : Good Job ! 2093 Words   |  9 Pagesjourney to Africa. I admire the view, and take in the lush beauty of the surrounding scape as one who is eternally entranced by the wild beauty of such an untamed wilderness. The ivory colored clouds roll overhead in infinite cobalt skies, and an elephant trumpets somewhere to the east among the rocky hills. Crack! Crack! Crack! A rifle echoes, and another three shots are are repeated as the resonance echoes through the hills. I take my finger off the trigger and tuck the short barreled weaponRead MoreEssay on Animal Rights: Turning the Tables2311 Words   |  10 PagesAbraham Lincoln once said, â€Å"Whenever I hear anyone arguing for slavery, I feel a strong impulse to see it tried on him personally.† Many animal activists see a strong comparison between animals used for research or entertainment and slaves (Day, 1994). Every year millions of animals are killed while being used for testing and entertainment. Some may say that animals do not have emotions so using them for these types of activities is acceptable. In spite of that, a huge question that arises is whetherRead MoreModule Quizzes Essay14245 Words   |  57 Pagesthis course? All of these are steps to success in this class Module 2: Although the scientific method is based on the premise that every experiment can be repeated, very few experiments are actually repeated after their initial publication. Why? Money issues A researcher thinks that she has the cure for HIV. She is working with infected persons in small towns in Mexico and Africa. She has no approval from the Universities in either country, nor approval from the patients. Her data suggestsRead MoreBreastfeeding in Public3281 Words   |  14 Pagesreturn to making its own decisions and not having to worry about the feelings of those around us? It might be a blessing that there are many options available other than breastfeeding because options allow ease and freedom. With all the diseases and cancers striking women these days, options allow them to do everything from artificial insemination to adoption. The availability of options has the capability to cause unwanted stress. If breastfeeding in public grows to be a larger issue, what once was

The Scope Of Sexuality Education - 1975 Words

Introduction While a lot of medical attention is provided to individuals with developmental disability, little has been done to ensure that their sexual lifestyles are not affected. There are multiple barriers which include lack of attention by the common people as well as misconception about sexuality. It is often misunderstood that individuals with disabilities do not exhibit a desire and are incapable of having a sexual understanding of life, thus not able to fulfil their sexual needs (Murphy and Elias, 2006). In terms of quality of life, we have a different point of view which suggests that those having moderate to severe disabilities lack the skill which will lead to a socially sensitive quality of life, since they are behind in terms of education (Harader, Fullwood, and Hawthrone, 2009). A good way to bust these myths would be to create a definition of sexuality and the various associated components. There are various definitions available which try to provide a diverse avenue to the scope of sexuality education. There is little doubt that those with a superior access to education or information lead a fear-free life, away from verbal or physical abuse, various unplanned pregnancies or various sexually transmitted diseases (STD’s) (Murphy and Young, 2005). Research also shows that when it comes to opportunity, individuals with developmental disabilities are often not provided with the same (Boehning, 2006). On instances, access to such opportunity is deniedShow MoreRelatedSex Education : Encyclopedia Of Gender And Society946 Words   |  4 PagesConnell, Erin. Sex Education. Encyclopedia of Gender and Society. Ed. Jodi O Brien. Vol. 2. Thousand Oaks, CA: SAGE Publications, 2009. 745-748. Gale Virtual Reference Library. Web. 30 Sept. 2015. This article has a really good explanation and a history behind. Sex education began during the 19th and early 20th centuries. This type of education debate or reveals a range of attitudes, values and also belief about the children, adolescent, sexuality, and gender. During WWI soldiers were infectedRead MoreSexuality And Its Effect On Adolescent Life1601 Words   |  7 PagesA. Introduction Understanding about sexuality is very important in maintaining healthy sexual behavior. Limited understanding about sexuality will give negative effects on young adolescent life. There are several implications that are related with low of sexuality comprehension among young adolescent (1). One of the most important implication is that risk of infected by sexual transmitted infection through a risky sexual behavior. Adolescent are considered as an innocent and curious phase of humanRead MoreSexuality Within The Older Population1475 Words   |  6 Pages Sexuality within the Older Population Jonelle S. Allen LaSalle University Introduction Sexuality is an important core dimension of life that incorporates beliefs, cultures, rituals, attitudes, values, intimacy and pleasure. The expression of sexuality along with the desire for intimacy can be very complex especially for the older adult. Sexual dysfunction among older men and women commonly increases with age along withRead MoreThe Discussion Of Teaching Sex Education1558 Words   |  7 PagesThe discussion of teaching sex education in classrooms were brought up as early as 1912. Movies that are used in sex education can alter the way teens think of sex. The films used in sex education portrays the different relationships that are created. The history of sex education in North America is a history of prohibition and has been concerned with limiting the scope of sexuality its ideas, affects, movements and practices. In sex education schools create a space in which students and teachersRead MoreLaura J. Mcgough’S Gender, Sexuality, And Syphilis In Early1436 Words   |  6 PagesLaura J. McGough’s Gender, Sexuality, and Syphilis in Early Modern Venice opens immediately in the dawn of the 16th century, when France invaded Italy. This invasion brought diseases previously foreign to the area that immediately became linked to the French and the destruction of Italian institutions. McGough quickly defines the illness she will examine, which is not necessarily Syphilis as indicated in title. The disease is a more broadly encompassing ‘French disease’ and while frequently consideredRead MorePrejudice Against Women By Nancy Tuana And Young, White, And Miserable By Wini Breines1000 Words   |  4 Pagesallowing the thoughts and actions to become unnoticeable in the everyday workings of life. Unlike other forms of prejudice, prejudice against women finds support in several creation myths allowing its perpetuity. Conceptions of women s bodies and sexuality provide a basis for discrimination and men s control over women, and by exa mining The Less Noble Sex by Nancy Tuana and Young, White, and Miserable by Wini Breines, a conclusion about prejudice against women is attained. The perpetuity of prejudiceRead MoreThe Uc Davis Student Health And Counseling Services990 Words   |  4 Pagescycle of everyday life. Health education provides its population with the necessary knowledge and tools to help increase overall health, shape attitudes, and ultimately hopes to change behavior (WHO, n.d.). Health education is advocating, promoting, teaching, and setting an example of well-being for all human beings regardless of ethnicity, social economic status, race, and everything else that differentiates people from one another. The purpose of health education is to empower individuals to makeRead MoreShould Sex Education Be Incorporated Into Public Schools?1372 Words   |  6 PagesFor Sex Education in Public Schools An observation of the prevalent television programs and popular topics broadcasted in the media often depict teenagers with an air of promiscuity. Is teenage pregnancy really an uncontrolled epidemic, as depicted in shows such as â€Å"16 and Pregnant†? Are a vast majority of teenagers exchanging racy photos of their bodies with each other? If so, are teenagers acting out because of too much sex education? Or is the outbreak of hyper-sexualized activity linked to lackRead MoreSexting : A Deeper Understanding On The Issue Of Sexting1658 Words   |  7 Pagessimilarities in attitudes, behaviors and consequences of sexting as it relates to gender. Through innovative methods, technology provides an opportunity for people all over the world to connect and explore their sexuality. There is an interesting contemporary interaction between technology and sexuality as it relates to sexting. Sexting is the production and distribution of sexually explicit imaged through communication te chnologies (Walker, Sanci, Temple-Smith, 2013). Sexting has become more prevalentRead MoreSexuality Is A Social Identity That Goes Beyond The Objectivity1636 Words   |  7 PagesSexuality is a social identity that goes beyond the objectivity of the title and into the subjective scope of the personal lives of individuals, which in turn fabricate the social constructivism of a nation. Classism, heterosexism, and cisgenderism are further reinforced within the institutionalization of heteronormativity, being the promotion of the gender binary and heterosexuality as the only valid form of gender expression and sexual orientation. The normalization of this system is not enforced

American Sign Language Verus Oral Communication free essay sample

ASL can connect Deaf and hard of hearing people to hearing people by using an interpreter. Sign Language interpreters listen English and translate it into ASL. Those people who are Deaf or hard of hearing and need an interpreter for academic purposes, doctor appointments, job interviews, and conferences to name a few can request those services. Deaf and hard of hearing can request for an interpreters through the offices then offices request the interpreter from agency. For example, when I called doctor office to make an appointment and I requested an interpreter. Doctor office will call the agency for an interpreter. Doctor office is reasonable to call the agency to hire an interpreter. ASL also facilitates communicating with others who use ASL. Oral communication is refers to spoken verbal communication including speech, lip reading, and voice training. While some Deaf and hard of hearing people that have cochlear implants or hearing aids can communicate using ASL, others rely on oral communication. We will write a custom essay sample on American Sign Language Verus Oral Communication or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page They use oral communication to connect with their family and friends, for education and every day life in general. Oral communication may help them more than those who are dependent on ASL. I prefer to use American Sign Language because it is an easier for me to communicate and socialize with other deaf people. I feel more comfortable with the language ASL than English. I’m able to speak with hearing people, but I would rather use ASL. I always request an interpreter for my academics, doctor appointments and job interviews. I really enjoy teaching hearing people sign language. Deaf and hard of hearing people have two ways of communicating with their own advantages and preference. American sign language and oral communication are different communications. My goal to informed to the people aware of ASL how to use it.

Why Did William Win the Battle of Hastings Essay Sample free essay sample

In 1066 king Edward the confessor died without any kids to inherit the throne of England. this meant that Harold Godwinson was crowned as king despite supposidly assuring an curse to william that he would be the following male monarch. However harold faced his place being jeportised because two other determined immature work forces besides wanted to be King. These work forces were Harald Hadrarda and William of Normandy. England was one of the welthiest and most powerfull state in the universe and all 3 of these work forces were prepared to make whatever it took to derive the Crown. The lone manner to make up ones mind who was traveling to be king was to prosecute in conflict. Harold and william both prepared there forces. First Harald hardra from norway invaided England with his viking fleet and fought against harold godwinson at Stanford span. After the Battle of Stamford Bridge ( In which Harald had died. We will write a custom essay sample on Why Did William Win the Battle of Hastings? Essay Sample or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page ) Harold had intelligence that william had eventually invaided and went down to Hastingss to fix to contend William. but this was traveling to be tough. both work forces were despairing to be following King and at that place could merely be one victor. In my sentiment the chief ground to why william won was pinned on fortune. Harold eagarly anticipating this to go on and he and his ground forces waited on the beach strong and prepared for the Norman invaison. William was be aftering to get on the beach and if this had happened Harold would hold slaughtered him. Fortunately for William. the sea was excessively jerky to sail across the channel and so William’s ground forces were waiting in Normandy for the conditions to better before traversing. Luckily for william Hadrada invaided up north and hence Harold went up north. Harold so fought a conflict go forthing his ground forces in a much weaker place than earlier. A major ground to why harold doomed was due to his ground forces was exhausted and weakened in Numberss. The conflict of Stanford span was a ghastly 1 with the Norwegians declining to give up untill the following twenty-four hours were Hardras boy Olav agreed to give himself up and neer return to england. The arm so rested. some beginnings claim that harold had an statement with his ground forces claiming that ahrold had non shared the trophies of conflict out reasonably. prehaps he had insisted on maintaining the Viking fleet which would hold been a enormous